IMBALANCE OF BLOOD SUGAR IS A GLOBAL HEALTH CARE PROBLEM THAT TREATABLE DISEASE AFFECTING ABOUT 200 MILLION PEOPLE AROUND THE WORLD [1]. ALTHOUGH THERE ARE MANY DIFFERENT METHODS FOR GLUCOSE DETERMINATION, BUT ELECTROCHEMICAL METHODS HAVE ABSORPTION MORE CONCENTRATION DUE TO THEIR SIMPLICITY, PROPER SELECTIVITY AND HIGH SENSITIVITY [2]. IN THIS STUDY, SENSITIVE AND STABLE NON-ENZYMATIC GLUCOSE SENSOR BASED ON GO/NC/CUO COMPOSITE PASTE ELECTRODE WAS FABRICATED. THE MORPHOLOGY OF NANOMATERIAL AND NANOCOMPOSIT WERE INVESTIGATED BY SCANNING ELECTRON MICROSCOPY (SEM), TRANSMISSION ELECTRON MICROSCOPY (TEM) AND XRAY DIFFRACTION(XRD).CYCLIC VOLTAMMETRY AND AMPEROMETRY WERE PERFORMED TO STUDY THE ELECTROCATALYTIC OXIDATION OF GLUCOSE IN ALKALINE MEDIUM AT GO/NC/CUO-CPE. A LINER RANG OF 0.05 TO 30 MM GLUCOSE, LIMIT OF DETECTION 2.5MM (SIGNAL-TO-NOISE 3) WERE OBSERVED. THE MODIFIED ELECTRODES OFFER EXCELLENT ELECTRO CATALYTIC ACTIVITY TOWARD THE GLUCOSE OXIDATION AT LOW POSITIVE POTENTIAL (0.4 V VS AG/AGCL). AS A RESULT, IT COULD BE CONCLUDED THAT GO/NC/CUO-CPE AT PRESENCE OF NC WOULD PAVE THE WAY FOR GLUCOSE BIOSENSOR. THE NOVEL GLUCOSE SENSOR ALSO EXHIBITS GOOD REPRODUCIBILITY, LONG-TERM STABILITY, AS WELL AS NO INTERFERENCE FROM L-ASCORBIC ACID, URIC ACID, FRUCTOSE AND GALACTUS, SO IT IS REASONABLE TO EXPECT ITS BROAD USE IN NON-ENZYMATIC GLUCOSE SENSOR.

CELLULOSE IS THE MOST ABUNDANT AND RENEWABLE NATURAL BIOPOLYMER PROVIDED BY NATURE. DURING THE LAST DECADE, THERE HAS BEEN A GROWING INTEREST IN THE USE OF NANOSIZED CELLULOSE. REGARDING ITS CHEMICAL STRUCTURE, NANOCELLULOSE (NC) HAS MANY ACTIVE HYDROXYL GROUPS, WHICH CAN BE MODIFIED BY DIFFERENT MOLECULES FOR VARIOUS APPLICATIONS. BIOCIDE ACTIVITY IS AN IMPORTANT PROPERTY THAT CAN BE ACHIEVED BY MODIFICATION OR CONJUGATION OF NANOCELLULOSE WITH DIFFERENT ANTIMICROBIAL AGENTS SUCH AS ORGANIC COMPOUNDS, METAL NANOPARTICLES AND METAL OXIDE NANOPARTICLES. COMPOUNDS CONTAINING BENZOTHIAZOLE RING POSSESS POTENT AND SELECTIVE BIOLOGICAL ACTIVITIES SUCH AS ANTIBACTERIAL, ANTIFUNGI AND ANTI-INFLAMMATORY [3]. THE PRESENT STUDY WAS CONDUCTED TO DETERMINE WHETHER THE NANOCELLULOSEPOSSESSED BIOLOGICAL ACTIVITY WHEN CHEMICALLY BONDED TO A BIOACTIVE ORGANIC COMPOUND. FOR THIS GOAL, WE USE A BIFUNCTIONAL REAGENT OF (3-ISOCYANATOPROPYL) TRIETHOXYSILANE (ICPTES) AS THE COUPLING AGENT TO CHEMICALLY FIX 2-AMINOBENZOTHIAZOLE ONTO CELLULOSE. THE STRUCTURE OF PRODUCTS1 AND 2 WAS CONFIRMED BY IR, 1H AND 13C NMR SPECTROSCOPY ANDSCANNING ELECTRON MICROSCOPY (SEM).

IN THIS STUDY, MAGNETIC NANOCELLULOSE/HALLOYSITE NANOTUBES COMPOSITE M (NC/HNTS) WAS PERFORMED FOR NICKEL IONS REMOVAL FROM AQUEOUS SOLUTION. IN THE FIRST STEP, MAGNETIC IRON OXIDE (FE3O4) NANOPARTICLES WERE PREPARED BY A CHEMICAL CO-PRECIPITATION METHOD AND THEN, M (NC/HNTS) COMPOSITE WAS SYNTHESIZED...